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Symbol
Name
ID
Brdt
bromodomain, testis-specific
MGI:1891374
Phenotype annotations related to reproductive system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Acephalic spermatozoa
Reduced sperm motility
Male infertility
Disease(s) Associated with BRDT
spermatogenic failure 21

Mouse Phenotypes
reproductive system phenotype
abnormal sperm flagellum morphology
abnormal sperm midpiece morphology
azoospermia
oligozoospermia
teratozoospermia
abnormal sperm head morphology
abnormal acrosome assembly
abnormal spermatid morphology
abnormal spermatocyte morphology
arrest of male meiosis
increased male germ cell apoptosis
asthenozoospermia
abnormal male accessory sex gland morphology
abnormal seminiferous tubule morphology
decreased testis weight
abnormal spermatogenesis
delayed sexual maturation
male infertility
Availability Mouse Genotype
Brdttm1a(EUCOMM)Wtsi/Brdttm1a(EUCOMM)Wtsi
Brdttm1Djw/Brdttm1Djw *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory